| Home | E-Submission | Sitemap | Contact Us |  
top_img
Journal of Environmental Toxicology 2005;20(2):143-151.
UV-B 조사로 유도된 접촉 과민반응에 대한 홍삼과 홍삼+EGb 761 혼합물의 억제 효과 비교
최욱희, 김덕성, 안형수, 이영미, 안령미
Combined Effect of Korean Red Ginseng and EGb 761 on Ultraviolet B-induced Contact Hypersensitivity
Wookhee Choi , Duksung Kim , Hyoungsoo Ann , Youngmi Lee , Ryoungme Ahn
ABSTRACT
Exposure of skin to UV-B radiation can cause inflammatory response and immunosuppression. It has been reported that Korean Red Ginseng (KRG) has several pharmacological and physiological effects such as antioxidant, anticancer and improving immune function. In this study, we investigated that topical KRG and KRG±EGb 761 (Ginkgo biloba extract) combination prevented UV-B induced inflammation and inhibition of contact hypersensitivity response. Topical application of KRG, 5 days prior to or 5 days after exposure to 1MED and 2MED of UV-B, reduced skin thickness compared to non-treated group and resulted in protection against immunosuppression. However, KRG±EGb 761 combination has a little protection against the only 1MED UV-B. In conclusion. Topical application of KRG was more effective than combination in protection against UV-B induced inflammation and immune suppression. Also, we suggest that KRG can provide protection from inflammation and immunosuppression by UV-B radiation.
TOOLS
PDF Links  PDF Links
Full text via DOI  Full text via DOI
Download Citation  Download Citation
CrossRef TDM  CrossRef TDM
Share:      
METRICS
1,940
View
3
Download
Editorial Office
Division of Environmental Science and Ecological Engineering, Korea University
145 Anam-ro, Seongbuk-gu, Seoul 02841, Korea
Tel : +82-32-560-7520   E-mail: envitoxic@gmail.com
About |  Browse Articles |  Current Issue |  For Authors and Reviewers
Copyright © 2023 by The Korean Society of Environmental Health and Toxicology & Korea Society for Environmental Analysis.     Developed in M2PI